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1

Structure–activity relationship of cardiotonic flavonoids in guinea-pig papillary muscle

Masataka Itoigawa, Kazumi Takeya, Chihiro Ito, Hiroshi Furukawa

Journal:

Journal of Ethnopharmacology

Year:

1999

Language:

english

File:

PDF, 128 KB

english, 1999

2

Study of the structure-activity relationships of new dihydropyridine derivatives.

SUZUKI, Kunio, NAGURA, Jun, SHIRATORI, Kenji, MURAYAMA, Bunsei, HARADA, Nobuo, MIYANO, Tetsuji, TAKEYA, Kazumi

Journal:

Journal of Pharmacobio-Dynamics

Year:

1989

File:

PDF, 630 KB

1989

3

Studies on cardiac ingredients of plants. (IV). Effect of reduced proscillaridins on guinea-pig hearts.

SAKAKIBARA, Jinsaku, MORI, Jun, NAGAI, Shin-ichi, HOTTA, Yoshihiro, TAKEYA, Kazumi

Journal:

Folia Pharmacologica Japonica

Year:

1987

File:

PDF, 6.24 MB

1987

4

Different effects of isoproterenol and dihydroouabain on cardiac Ca2+ transients

Yoshihiro Hotta, Hiroaki Ando, Michiko Fujita, Junichi Nakagawa, Kazumi Takeya, Jinsaku Sakakibara

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 882 KB

english, 1995

5

Osimertinib for patients with EGFR T790M mutation-positive non–small-cell lung cancer and a poor performance status

Nakashima, Kazuhisa, Kimura, Madoka, Akamatsu, Hiroaki, Daga, Haruko, Imai, Hisao, Taira, Tetsuhiko, Ko, Ryo, Hisamatsu, Yasushi, Nishino, Kazumi, Sugimoto, Takeya, Miyashita, Yosuke, Takahashi, Toshi

Journal:

Japanese Journal of Clinical Oncology

Year:

2019

Language:

english

File:

PDF, 396 KB

english, 2019

6

Studies on Cardiac Ingredients of Plants. VII. Chemical Transformation of Proscillaridin by Means of the Diels-Alder Reaction and Biological Activities of Its Derivatives.

MURAKAMI, Nobutoshi, TANASE, Takahiro, NAGAI, Shin-ichi, SATO, Yuichi, UEDA, Taisei, SAKAKIBARA, Jinsaku, ANDO, Hiroaki, HOTTA, Yoshihiro, TAKEYA, Kazumi

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1991

File:

PDF, 845 KB

1991

7

Studies on Cardiac Ingredients of Plants. X. Preparation of Nitrates of Tetrahydroproscillaridin and Their Pharmacological Activides

TANASE, Takahiro, MURAKAMI, Nobutoshi, NAGATSU, Akito, NAGAI, Shin-ichi, SAKAKIBARA, Jinsaku, ANDO, Hiroaki, HOTTA, Yoshihiro, TAKEYA, Kazumi, ASANO, Masahisa

Journal:

YAKUGAKU ZASSHI

Year:

1992

File:

PDF, 1.02 MB

1992

8

DIFFERENCES IN SPEED AND DEGREE OF MYOSIN B SUPERPRECIPITATION IN THE PRESENCE OF DIVALENT CATIONS

YAJIMA, Michio, TAKEYA, Kazumi

Journal:

The Japanese Journal of Pharmacology

Year:

1979

Language:

english

File:

PDF, 189 KB

english, 1979

9

Triphasic inotropic response of guinea-pig papillary muscle to murrayaquinone-A isolated from Rutaceae

Kazumi Takeya, Masataka Itoigawa, Hiroshi Furukawa

Journal:

European Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 520 KB

english, 1989

10

Cardiotonic Flavonoids from Citrus Plants (Rutaceae).

ITOIGAWA, Masataka, TAKEYA, Kazumi, FURUKAWA, Hiroshi

Journal:

Biological & Pharmaceutical Bulletin

Year:

1994

File:

PDF, 447 KB

1994

11

Studies on Cardiac Ingredients of Plants. XI. Synthesis of New Bufotoxin Homologues Utilizing Scillarenin (the Genuine Aglycone of Proscillaridin), and Their Biological Activities.

TANASE, Takahiro, NAGATSU, Akito, MURAKAMI, Nobutoshi, NAGAI, Shin-ichi, UEDA, Taisei, SAKAKIBARA, Jinsaku, ANDO, Hiroaki, HOTTA, Yoshihiro, TAKEYA, Kazumi, ASANO, Masahisa

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1994

File:

PDF, 939 KB

1994

12

Studies on Cardiac Ingredients of Plants. VIII. Preparation of Nitrates of Proscillaridin and Their Pharmacological Activities

MURAKAMI, Nobutoshi, SATO, Yuichi, TANASE, Takahiro, NAGAI, Shinichi, UEDA, Taisei, SAKAKIBARA, Jinsaku, ANDO, Hiroaki, HOTTA, Yoshihiro, TAKEYA, Kazumi, ASANO, Masahisa

Journal:

YAKUGAKU ZASSHI

Year:

1991

File:

PDF, 923 KB

1991

13

Inhibition of dopamine β-hydroxylase by fusaric acid (5-butylpicolinic acid) in vitro and in vivo

Nagatsu Toshiharu, Hidaka Hiroyoshi, Kuzuya Hiroshi, Takeya Kazumi, Umezawa Hamao, Takeuchi Tomio, Suda Hiroyuki

Journal:

Biochemical Pharmacology

Year:

1970

Language:

english

File:

PDF, 730 KB

english, 1970

14

Studies on cardiac ingredients of plants. III. Structural confirmation and biological activity of reduced proscillaridins.

MORI, JUN, NAGAI, SHIN-ICHI, SAKAKIBARA, JINSAKU, TAKEYA, KAZUMI, HOTTA, YOSHIHIRO, ANDO, HIROAKI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1987

Language:

english

File:

PDF, 1.13 MB

english, 1987

15

Studies on Cardiac Ingredients of Plants. XIII. Chemical Modification of Gitoxin to Cardiotonic Compounds without Vascular Contractile Effect.

NAGATSU, Akito, NAKAMURA, Yukitaka, TAKEMOTO, Kouya, SHIBATOMI, Kazutaka, NAGAI, Shin-ichi, UEDA, Taisei, SAKAKIBARA, Jinsaku, HIDAKA, Hiroyoshi, FUJITA, Michiko, HOTTA, Yoshihiro, TAKEYA, Kazumi, ASA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1997

File:

PDF, 1.38 MB

1997

16

Studies on the chemical modification of monensin. II. Measurement of sodium ion pemeability of monensylamino acids using sodium-23 nuclear magnetic resonance spectroscopy.

NAKAMURA, Akito, NAGAI, Shin-ichi, UEDA, Taisei, SAKAKIBARA, Jinsaku, HOTTA, Yoshihiro, TAKEYA, Kazumi

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1989

File:

PDF, 622 KB

1989

17

Studies on Cardiac Ingredients of Plants : Biological Activities and Structural Variation of Xanthines

SAKAKIBARA, JINSAKU, UEDA, TAISEI, OHSAKI, TSUTOMU, TAKEYA, KAZUMI, ANDO, SAWAKO

Journal:

YAKUGAKU ZASSHI

Year:

1985

File:

PDF, 623 KB

1985

18

Relaxing Effect of Vesnarinone (OPC-8212) on the Tracheal Muscle Strips Isolated from Guinea Pigs.

Takeya, Kazumi, Ando, Hiroaki, Ando, Sawako, Yajima, Michio, Nomura, Hirohiko

Journal:

The Japanese Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 496 KB

english, 1993

19

O2-11-5Osimertinib for patients with EGFR T790M mutation-positive non-small-cell lung cancer who have poor performance status

Kimura, Madoka, Nishino, Kazumi, Imamura, Fumio, Nakashima, Kazuhisa, Takahashi, Toshiaki, Sugimoto, Takeya, Akamatsu, Hiroaki, Yamamoto, Nobuyuki, Daga, Haruko, Imai, Hisao, Taira, Tetsuhiko, Miyashi

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 77 KB

2018

20

Frequent presence of HBV in the sera of HBsAg-negative, anti-HBc-positive blood donors

Hiroshi Yotsuyanagi, Kiyomi Yasuda, Kyoji Moriya, Yoshizumi Shintani, Hajime Fujie, Takeya Tsutsumi, Noriyoshi Nojiri, Takeo Juji, Hiromi Hoshino, Kazumi Shimoda, Kunihiko Hino, Satoshi Kimura, Shiro

Journal:

Transfusion (Wiley)

Year:

2001

Language:

english

File:

PDF, 280 KB

english, 2001

21

Protective Effect of SM-20550, a Selective Na+-H+ Exchange Inhibitor, on Ischemia-Reperfusion-Injured Hearts

Hotta, Yoshihiro, Nakagawa, Junichi, Ishikawa, Naohisa, Wakida, Yasushi, Ando, Hiroaki, Takeya, Kazumi, Ohashi, Naohito, Matsui, Kazuki

Journal:

Journal of Cardiovascular Pharmacology

Year:

2001

Language:

english

File:

PDF, 944 KB

english, 2001

22

Blood Pressure Decreased by Halobutylpicolinic Acid, an Inhibitor of Dopamine β-Hydroxylase

HIDAKA, HIROYOSHI, TAKEYA, KAZUMI

Journal:

Year:

1972

File:

PDF, 224 KB

1972

23

FUSARIC ACID, A HYPOTENSIVE AGENT PRODUCED BY FUNGI

HIDAKA, HIROYOSHI, NAGATSU, TOSHIHARU, TAKEYA, KAZUMI, TAKEUCHI, TOMIO, SUDA, HIROYUKI, KOJIRI, KATSUHISA, MATSUZAKI, MEIKI, UMEZAWA, HAMAO

Journal:

The Journal of Antibiotics

Year:

1969

Language:

english

File:

PDF, 401 KB

english, 1969

24

23Na-NMR measurements of the sodium concentration in guinea pig erythrocytes: The effects of cardiac glycoside and asebotoxin III.

HOTTA, Yoshihiro, ANDO, Hiroaki, ETO, Ryo, TAKEYA, Kazumi, HARUNA, Mitsumasa, ITO, Kazuo, SAKAKIBARA, Jinsaku

Journal:

Folia Pharmacologica Japonica

Year:

1992

File:

PDF, 1.05 MB

1992

25

Quantitative structure-inotropy relationship applied to substituted grayanotoxins

Shirai, Naohiro, Sakakibara, Jinsaku, Kaiya, Toyo, Kobayashi, Sawako, Hotta, Yoshihiro, Takeya, Kazumi

Journal:

Journal of Medicinal Chemistry

Year:

1983

Language:

english

File:

PDF, 602 KB

english, 1983

26

Cardiotonic Action of Plumbagin on Guinea-Pig Papillary Muscle

Itoigawa, Masataka, Takeya, Kazumi, Furukawa, Hiroshi

Journal:

Year:

1991

Language:

english

File:

PDF, 184 KB

english, 1991

27

Mode of Cardiotonic Action of Helenalin, a Sesquiterpene Lactone, on Guinea Pig Ventricular Myocardium

Itoigawa, Masataka, Takeya, Kazumi, Kazuo Ito, Hiroshi Furukawa

Journal:

Journal of Cardiovascular Pharmacology

Year:

1987

File:

PDF, 634 KB

1987

28

Effect of divalent manganese ions on action potential and contractility of cardiac muscle

Kazumi Takeya, Melchior Reiter

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1972

Language:

english

File:

PDF, 830 KB

english, 1972

29

Positive inotropic effect of helenalin, a sesquiterpene lactone, on guinea-pig myocardium.

TAKEYA, KAZUMI, ITOIGAWA, MASATAKA, FURUKAWA, HIROSHI

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1983

File:

PDF, 688 KB

1983

30

Cardiovascular effects of NPK-1886, a new dihydropyridine compound with calcium entry blocking activity.

NAGURA, Jun, MURAYAMA, Bunsei, HARADA, Nobuo, SUZUKI, Kunio, MIYANO, Tetsuji, YAJIMA, Michio, TAKEYA, Kazumi

Journal:

The Japanese Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 746 KB

english, 1986

31

Protective effects of dimethyl amiloride against postischemic myocardial dysfunction in rabbit hearts: Phosphorus 31—nuclear magnetic resonance measurements of intracellular pH and cellular energy

Akira Koike, Toshiaki Akita, Yoshihiro Hotta, Kazumi Takeya, Itsuo Kodama, Mitsuya Murase, Toshio Abe, Junji Toyama

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

1996

Language:

english

File:

PDF, 949 KB

english, 1996

32

Relationship between the inotropy speeds in guinea-pig myocardium and lipophilic character of cardenolides and ericaceous toxins.

HOTTA, Yoshihiro, ANDO, Hiroaki, SHIRAI, Naohiro, SAKAKIBARA, Jinsaku, TAKEYA, Kazumi

Journal:

The Japanese Journal of Pharmacology

Year:

1984

Language:

english

File:

PDF, 821 KB

english, 1984

33

Direct measurement of increased myocardial cellular23Na NMR signals in perfused guinea-pig heart induced by dihydroouabain and grayanotoxin-I

Yoshihiro Hotta, Hiroaki Ando, Kazumi Takeya, Jinsaku Sakakibara

Journal:

Molecular and Cellular Biochemistry

Year:

1994

Language:

english

File:

PDF, 993 KB

english, 1994

34

Studies on the influence of potassium concentration to the interaction between actomyosin and ATP

Journal:

Folia Pharmacologica Japonica

Year:

1961

File:

PDF, 1.73 MB

1961

35

Studies on cardiac ingredients of plants. V. Chemical transformation of proscillaridin and biological activities of derivatives.

MORI, JUN, NAGAI, SHIN-ICHI, SAKAKIBARA, JINSAKU, TAKEYA, KAZUMI, HOTTA, YOSHIHIRO

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

File:

PDF, 1.07 MB

1988

36

Asebotoxin-induced centrogenic pulmonary hemorrhage in guinea pigs.

TAKEYA, Kazumi, HOTTA, Yoshihiro, HARADA, Nobuo, ITOH, Gen, SAKAKIBARA, Jinsaku

Journal:

The Japanese Journal of Pharmacology

Year:

1981

Language:

english

File:

PDF, 295 KB

english, 1981

37

Pro-B-type natriuretic peptide is cleaved intracellularly: impact of distance between O -glycosylation and cleavage sites

Nishikimi, Toshio, Nakagawa, Yasuaki, Minamino, Naoto, Ikeda, Masashi, Tabei, Kyoko, Fujishima, Aoi, Takayama, Kentaro, Akimoto, Kazumi, Yamada, Chinatsu, Nakao, Kazuhiro, Minami, Takeya, Kuwabara, Yo

Journal:

AJP Regulatory Integrative and Comparative Physiology

Year:

2015

Language:

english

File:

PDF, 319 KB

english, 2015

38

Studies on Cardiac Ingredients of Plants. IX. Chemical Transformation of Proscillaridin by Utilizing Its 1,4-Cycloadducts as Key Compounds and Biological Activities of Their Derivatives.

TANASE, Takahiro, MURAKAMI, Nobutoshi, NAGAI, Shin-ichi, UEDA, Taisei, SAKAKIBARA, Jinsaku, ANDO, Hiroaki, HOTTA, Yoshihiro, TAKEYA, Kazumi

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1992

File:

PDF, 986 KB

1992

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